[PRECELLYS] Binding of one lipophilic compound to the Precellys tubes with ceramic beads during tissue homogenization - Bertin Technologies

[PRECELLYS] Binding of one lipophilic compound to the Precellys tubes with ceramic beads during tissue homogenization

Sources: Songmao Zheng, Justina C. Calamia, Departments of Pharmaceutics,University of Washington, Seattle, WA, USA

Context

To study lipophilic compounds glass vials are widely used in labs. We were aiming to quantify the loss of one lipophilic compound in the tissue homogenization process using Precellys tubes with ceramic beads. For that, we selected one compound that shown to bind plastic extensively. The compound info is: small molecule; neural compound; MW>500; experimental / theoretical LogP >3; low water solubility.

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