Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages

Karine Labadie,1,2 Thibaut Larcher,3 Christophe Joubert,1,2 Abdelkrim Mannioui,1,2 Benoit Delache,1,2Patricia Brochard,1,2 Lydie Guigand,3 Laurence Dubreil,3 Pierre Lebon,4 Bernard Verrier,5Xavier de Lamballerie,6,7 Andreas Suhrbier,8 Yan Cherel,3 Roger Le Grand,1,2 and Pierre Roques1,2

Sources: 1CEA, Division of Immuno-Virology/Institute of Emerging Diseases and Innovative Therapies (iMETI), Fontenay-aux-Roses, France. 2UMR-E1, Paris-Sud 11, Orsay, France. 3INRA, UMR 703, Ecole Nationale Vétérinaire, Nantes, France. 4Université Paris V, Hôpital Cochin-St Vincent de Paul, Service de virologie, Paris, France. 5CNRS, UMR 5086, IBCP-IFR 128, Lyon, France. 6Université de la Méditerranée, Unité des Virus Emergents, Marseille, France.7Institut de Recherche pour le Développement, Marseille, France. 8Australian Centre for International and Tropical Health, Queensland Institute of Medical Research, Brisbane, Australia.

J Clin Invest. 2010;120(3):894-906. doi:10.1172/JCI40104.The Journal of Clinical Investigation http://www.jci.org Volume 120 Number 3 March 2010