Context
Obtaining single primary cells from tissues is essential for advancing research in cell biology. Efficient tissue dissociation while preserving cell viability and integrity is critical for downstream applications, including single-cell analysis and therapeutic development. However, achieving optimal dissociation remains a challenge, particularly when working with complex organ tissues.
In this context, different options are available on the market based on mechanical and/or chemical approaches, and the “Competitor M” solution represent the reference so far. The Precellys Multi-Tissue Dissociation kit offers an innovative solution for dissociating various tissue types into single cells.
To assess its performance, we conducted a comparative study between both methods using mouse, heart, lung, spleen, and liver tissues.
