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Context
A sensitive, accurate and precise bioanalytical method was developed for the determination of Cidofovir diphosphate in monkey and rabbit tissues using LCMS/ MS. The method was developed to evaluate concentration levels of the active metabolite in various monkey and rabbit organs and tissues in support of a maximum tolerated dose study [1].
[1] Foley S, Begley J, Karnik S, Keilholz L, Lambert B. DirectQuantitative Determination ofCidofovir Diphosphate in Monkey and Rabbit Tissues using LC/MSMS.2012 ASMS meetingabstracts.
