Context
The West Midlands Regional Genetics Laboratory (WMRGL) is an NHS diagnostic laboratory providing testing for a wide range of genetic disorders. Fetal and perinatal pathology tissue samples are analyzed for chromosome abnormalities by QF-PCR and subtelomere MLPA. Prior to the introduction of the Precellys®24 these tissue samples were finely chopped using a scalpel, digested for >24 hours followed by a manual salting out DNA extraction procedure.