[PRECELLYS] Effective and automated pulverization of mouse muscle using the precellys evolution

Homogeneous, small particle powders are important to obtain the highest yield of metabolites extracted from tissues for metabolomics experiments. This is especially important when tissue powder from the same tissue needs to be aliquoted and homogenized in different extraction solvents to quantitate different classes of metabolites. The purpose of this study was to explore the utility of the Precellys Evolution to efficiently provide uniform, finely ground powders from difficult to grind tissues like mouse gastrocnemius compared to common methods like cryogrinding in a mortal and pestle.