Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia

1. Martina Weber*, 2. Sandro Lambeck†, 3. Nadine Ding∥, 4. Stefanie Henken∥, 5. Matthias Kohl*, 6. Hans P. Deigner¶, 7. David P. Enot¶, 8. Emeka I. Igwe¶, 9. Lucien Frappart#, 10. Michael Kiehntopf‡, 11. Ralf A. Claus*,†, 12. Thomas Kamradt§, 13. Debra Weih**, 14. Yoram Vodovotz††‡‡, 15. David E. Briles§§, 16. Abiodun D. Ogunniyi∥∥, 17. James C. Paton∥∥, 18. Ulrich A. Maus∥ and 19. Michael Bauer*,†,2

Sources: 1. *Department of Anaesthesiology and Intensive Care Therapy, 2. †Center for Sepsis Control and Care, 3. ‡Institute for Clinical Chemistry and Laboratory Medicine, and 4. §Institute of Immunology, Jena University Hospital, Jena, Germany; 5. ∥Department of Experimental Pneumology, Hannover School of Medicine, Hannover, Germany; 6. ¶Biocrates Life Sciences AG, Innsbruck; Austria; 7. #Department of Pathology, University Claude Bernard Lyon I and Inserm U590, Lyon, France; 8. **Leibniz Institute for Age Research, Fritz-Lipmann Institute, Jena, Germany; 9. ††Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; 10. ‡‡Center for Inflammation and Regenerative Modeling, McGowan Institute for Regenerative Medicine, Pittsburgh, Pennsylvania, USA; 11. §§Department of Microbiology,, University of Alabama at Birmingham, Alabama, USA; 12. ∥∥Research Centre for Infectious Diseases, School of Molecular and Biomedical Science, University of Adelaide, Adelaide, Australia

Published online before print March 13, 2012, doi: 10.1096/fj.11-191957 fj.11-191957