[PRECELLYS] Homogenization and extraction of fluorescent chemical compounds from mouse bone tissue - Bertin Technologies

[PRECELLYS] Homogenization and extraction of fluorescent chemical compounds from mouse bone tissue

Sources: Atlanthera Laboratories, Saint-Herblain, France

Context

Atlanthera is a drug discovery company specialized in bone-targeted drug delivery through covalent binding of drugs to hydroxybisphosphonates (HBP), a class of molecule known for high affinity to bone. Extraction of HBP-conjugated chemical from bone is challenging and require efficient tissue homogenization. Precellys® Evolution system was tested for bone homogenization and compared with a cryogenic grinder.

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