[PRECELLYS] Lipid hydroperoxides (LPO) extraction from frozen rat tumors, intestine, liver, and heart tissuessues

The fundamental and clinical project of our research unit is positioned at the junction of the two fields “cancer and nutrition” with a specialization in lipid biochemistry and breast cancer. Our research unit has described the potential benefit of the clinical use of lipid nutrients in order to increase the efficiency of cancer treatment. Docosahexaenoic acid (DHA) has the potential to increase tumor sensitivity to chemotherapy with no sensitization of normal tissues. This study [1] was aimed at exploring the mechanism involved in this differential sensitization with a focus on oxidative stress, one of the main determinants involved in DHA enhancement of anthracycline-based chemotherapy.