Context
The research focus of our laboratory is on human herpes virus pathogenesis and the development of new treatments and vaccines. We often need to test herpes simplex viruses (HSV) and their mutants in a mouse model to study the function of viral genes, evaluate antiviral therapies, and assess the efficacy of vaccine candidates. The titer of infectious HSV in the sensory nerve ganglion innervating the inoculation site is a crucial measurement for these studies.