homogenizer

In the third application note of our “Mastering Tissue Dissociation” series, we explored liver tissue dissociation to isolate single cells. Using liver samples from mice housed in standard conditions (UAR BioMedTech Facilities), we achieved a cell viability rate of 84.35%. This method ensures cell integrity, providing high-quality suspensions for liver research. Bertin Technologies’ Precellys Multi […]

In this study, researchers examine the effects of two drugs, everolimus and metformin, on triple-negative breast cancer.  Everolimus blocks a protein called mTOR, while metformin blocks part of the mitochondria, the energy powerhouses of cells. They found that everolimus reduced products of the tricarboxylic acid (TCA) cycle, a key energy-producing process, and inhibited an enzyme called pyruvate […]

Obtaining viable single cells from lung tissue is essential for understanding respiratory function and disease mechanisms. Despite its importance, isolating these cells remains challenging. Bertin Technologies’ Precellys Multi Tissue Dissociation kit, in conjunction with the Precellys Evolution Touch (or Precellys Evolution), offers an effective solution for dissociating lung tissues into single cells. In our recent […]

The dissociation of mouse heart tissue into single cells is a crucial step in many biomedical investigations. However, obtaining viable cells remains a challenge. Bertin Technologies’ Precellys multi-tissue dissociation kit, combined with the Precellys Evolution Touch, offers an effective solution to this problem. Our recent application note demonstrated a cell viability rate of 87.35%, proving […]

Worldwide obesity is a growing health problem, linked with an increased risk of associated chronic disease. Today, the World Health Organization is even speaking “about – globesity – and if immediate action is not taken, millions will suffer from an array of serious health disorders”. As the general public and international authorities slowly start to […]

Bertin Instruments will attend PITTCON Conference & Expo 2017, the world’s leading annual conference and exhibition on laboratory science to showcase its new InCellis Cell Imager and Precellys tissue homogenizers at the McCormick Place (West Hall), booth #938, from 5 to 9 March. About InCellis Cell Imager: Cell biologists need to generate cell images in […]

With more than several thousand publications in under two years, CRISPR-Cas9 revolutionized the science world and more particularly cellular and molecular biology. CRISPR-Cas9 technology allows genetic editing through mutation. For example, this leads to the generation of Knock-In or Knock-Out mice for animal studies [1]. Introducing mutation requires some controls to check the validity and […]