homogenizer

The rise of fentanyl and its analogs has led to a major public health crisis, making reliable detection methods essential for toxicology labs. Our latest Application Note presents an optimized workflow for analyzing synthetic opioids in hair samples, using the Precellys homogenizer and Bertin’s lysing kit. A Major Analytical Challenge Fentanyl is 50 times more […]

Tissue dissociation is a key step in many research areas. When working with complex tissues, it is essential to maintain cell viability while ensuring reliable results. This is particularly important for studies such as single-cell analysis, cell biology, and drug discovery. To assess performance, we recently compared the Precellys Multi-Tissue Dissociation Kit with the market […]

For researchers studying autosomal dominant polycystic kidney disease (ADPKD), accessing high-quality protein samples is essential for uncovering disease mechanisms and exploring therapeutic targets. The challenge lies in developing protocols that provide consistent and reproducible results while preserving sample integrity. The Precellys Evolution Touch tissue homogenizer has proven to be a reliable tool for addressing these needs. […]

Let Precellys take you from the dinner table to the lab with three essential Application Notes that showcase its versatility and efficiency for sample preparation. Whether you’re working with metabolomics, enzymatic activity, or DNA extraction, Precellys ensures that every step of your research is streamlined, reliable, and ready for success.   Appetizer:optimize metabolomic studies from […]

In the fourth and final application note of our “Mastering Tissue Dissociation” series, we focused on spleen tissue dissociation to isolate single cells. Using spleen samples from mice housed in standard conditions (UAR BioMedTech Facilities), we achieved a cell viability rate of 87.12%. This method preserves cell integrity, providing high-quality suspensions for spleen research. Bertin […]

In the third application note of our “Mastering Tissue Dissociation” series, we explored liver tissue dissociation to isolate single cells. Using liver samples from mice housed in standard conditions (UAR BioMedTech Facilities), we achieved a cell viability rate of 84.35%. This method ensures cell integrity, providing high-quality suspensions for liver research. Bertin Technologies’ Precellys Multi […]

In this study, researchers examine the effects of two drugs, everolimus and metformin, on triple-negative breast cancer.  Everolimus blocks a protein called mTOR, while metformin blocks part of the mitochondria, the energy powerhouses of cells. They found that everolimus reduced products of the tricarboxylic acid (TCA) cycle, a key energy-producing process, and inhibited an enzyme called pyruvate […]

Obtaining viable single cells from lung tissue is essential for understanding respiratory function and disease mechanisms. Despite its importance, isolating these cells remains challenging. Bertin Technologies’ Precellys Multi Tissue Dissociation kit, in conjunction with the Precellys Evolution Touch (or Precellys Evolution), offers an effective solution for dissociating lung tissues into single cells. In our recent […]

The dissociation of mouse heart tissue into single cells is a crucial step in many biomedical investigations. However, obtaining viable cells remains a challenge. Bertin Technologies’ Precellys multi-tissue dissociation kit, combined with the Precellys Evolution Touch, offers an effective solution to this problem. Our recent application note demonstrated a cell viability rate of 87.35%, proving […]

Worldwide obesity is a growing health problem, linked with an increased risk of associated chronic disease. Today, the World Health Organization is even speaking “about – globesity – and if immediate action is not taken, millions will suffer from an array of serious health disorders”. As the general public and international authorities slowly start to […]