Highlight the Everolimus metabolic effects on breast cancer
23 Oct 2024
In this study, researchers examine the effects of two drugs, everolimus and metformin, on triple-negative breast cancer. Everolimus blocks a protein called mTOR, while metformin blocks part of the mitochondria, the energy powerhouses of cells. They found that everolimus reduced products of the tricarboxylic acid (TCA) cycle, a key energy-producing process, and inhibited an enzyme called pyruvate […]