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Microplastics are not just contaminating oceans—they are also present in the air we breathe. However, detecting and quantifying these invisible particles remains a major scientific challenge. A recent study by Dimitri D. Deheyn, Joe Ayesu, The Or Foundation, and Branson Skinner at the Kantamanto market in Accra, Ghana, revealed an alarming concentration of 500 airborne […]

How to optimize bone sample preparation for metabolomics You know how crucial it is to reveal the hidden biochemical signatures in bone samples to unlock mysteries about past lifestyles and environmental exposures. Yet, complex bone matrices often lead to challenges that risk compromising your valuable material. Preserve sample integrity with advanced homogenization Precellys Evolution Touch […]

Challenges in Pharmaceutical Development Improving the dissolution, solubility, and bioavailability of poorly soluble drugs (BCS Class 2) remains a significant challenge. Amorphous Solid Dispersions (ASDs) are a promising solution, stabilizing drugs in their amorphous form using polymers and low-molecular-weight excipients. However, thermodynamic instability and complex processing steps make their preparation difficult. Limitations of Conventional Methods […]

The rise of fentanyl and its analogs has led to a major public health crisis, making reliable detection methods essential for toxicology labs. Our latest Application Note presents an optimized workflow for analyzing synthetic opioids in hair samples, using the Precellys homogenizer and Bertin’s lysing kit. A Major Analytical Challenge Fentanyl is 50 times more […]

Tissue dissociation is a key step in many research areas. When working with complex tissues, it is essential to maintain cell viability while ensuring reliable results. This is particularly important for studies such as single-cell analysis, cell biology, and drug discovery. To assess performance, we recently compared the Precellys Multi-Tissue Dissociation Kit with the market […]

Let Precellys take you from the dinner table to the lab with three essential Application Notes that showcase its versatility and efficiency for sample preparation. Whether you’re working with metabolomics, enzymatic activity, or DNA extraction, Precellys ensures that every step of your research is streamlined, reliable, and ready for success.   Appetizer:optimize metabolomic studies from […]

In the fourth and final application note of our “Mastering Tissue Dissociation” series, we focused on spleen tissue dissociation to isolate single cells. Using spleen samples from mice housed in standard conditions (UAR BioMedTech Facilities), we achieved a cell viability rate of 87.12%. This method preserves cell integrity, providing high-quality suspensions for spleen research. Bertin […]

In the third application note of our “Mastering Tissue Dissociation” series, we explored liver tissue dissociation to isolate single cells. Using liver samples from mice housed in standard conditions (UAR BioMedTech Facilities), we achieved a cell viability rate of 84.35%. This method ensures cell integrity, providing high-quality suspensions for liver research. Bertin Technologies’ Precellys Multi […]

In this study, researchers examine the effects of two drugs, everolimus and metformin, on triple-negative breast cancer.  Everolimus blocks a protein called mTOR, while metformin blocks part of the mitochondria, the energy powerhouses of cells. They found that everolimus reduced products of the tricarboxylic acid (TCA) cycle, a key energy-producing process, and inhibited an enzyme called pyruvate […]

The SAPHIR project, proposed in consortium with Prométhée Earth Intelligence, U-Space and the Marseille Astrophysics Laboratory (LAM), under the leadership of Bertin Technologies, has been awarded a share of the Plan France 2030 by the French Prime Minister. Its mission: Earth Observation for the benefit of the environment. Just over a year ago, as part […]