Precellys

Microplastics are not just contaminating oceans—they are also present in the air we breathe. However, detecting and quantifying these invisible particles remains a major scientific challenge. A recent study by Dimitri D. Deheyn, Joe Ayesu, The Or Foundation, and Branson Skinner at the Kantamanto market in Accra, Ghana, revealed an alarming concentration of 500 airborne […]

How to optimize bone sample preparation for metabolomics You know how crucial it is to reveal the hidden biochemical signatures in bone samples to unlock mysteries about past lifestyles and environmental exposures. Yet, complex bone matrices often lead to challenges that risk compromising your valuable material. Preserve sample integrity with advanced homogenization Precellys Evolution Touch […]

Challenges in Pharmaceutical Development Improving the dissolution, solubility, and bioavailability of poorly soluble drugs (BCS Class 2) remains a significant challenge. Amorphous Solid Dispersions (ASDs) are a promising solution, stabilizing drugs in their amorphous form using polymers and low-molecular-weight excipients. However, thermodynamic instability and complex processing steps make their preparation difficult. Limitations of Conventional Methods […]

The rise of fentanyl and its analogs has led to a major public health crisis, making reliable detection methods essential for toxicology labs. Our latest Application Note presents an optimized workflow for analyzing synthetic opioids in hair samples, using the Precellys homogenizer and Bertin’s lysing kit. A Major Analytical Challenge Fentanyl is 50 times more […]

Tissue dissociation is a key step in many research areas. When working with complex tissues, it is essential to maintain cell viability while ensuring reliable results. This is particularly important for studies such as single-cell analysis, cell biology, and drug discovery. To assess performance, we recently compared the Precellys Multi-Tissue Dissociation Kit with the market […]

For researchers studying autosomal dominant polycystic kidney disease (ADPKD), accessing high-quality protein samples is essential for uncovering disease mechanisms and exploring therapeutic targets. The challenge lies in developing protocols that provide consistent and reproducible results while preserving sample integrity. The Precellys Evolution Touch tissue homogenizer has proven to be a reliable tool for addressing these needs. […]

Let Precellys take you from the dinner table to the lab with three essential Application Notes that showcase its versatility and efficiency for sample preparation. Whether you’re working with metabolomics, enzymatic activity, or DNA extraction, Precellys ensures that every step of your research is streamlined, reliable, and ready for success.   Appetizer:optimize metabolomic studies from […]

The quality and efficiency of RNA and DNA extraction are essential factors in molecular biology research, diagnostics, and clinical applications. Whether in research laboratories, medical testing, or biotechnology facilities, optimizing RNA and DNA extraction protocols ensures reliable, high-quality results. The extraction techniques can vary based on the sample type and complexity, with methods including mechanical […]

In this study, researchers examine the effects of two drugs, everolimus and metformin, on triple-negative breast cancer.  Everolimus blocks a protein called mTOR, while metformin blocks part of the mitochondria, the energy powerhouses of cells. They found that everolimus reduced products of the tricarboxylic acid (TCA) cycle, a key energy-producing process, and inhibited an enzyme called pyruvate […]

Obtaining viable single cells from lung tissue is essential for understanding respiratory function and disease mechanisms. Despite its importance, isolating these cells remains challenging. Bertin Technologies’ Precellys Multi Tissue Dissociation kit, in conjunction with the Precellys Evolution Touch (or Precellys Evolution), offers an effective solution for dissociating lung tissues into single cells. In our recent […]