Sample Preparation

For researchers studying autosomal dominant polycystic kidney disease (ADPKD), accessing high-quality protein samples is essential for uncovering disease mechanisms and exploring therapeutic targets. The challenge lies in developing protocols that provide consistent and reproducible results while preserving sample integrity. The Precellys Evolution Touch tissue homogenizer has proven to be a reliable tool for addressing these needs. […]

Let Precellys take you from the dinner table to the lab with three essential Application Notes that showcase its versatility and efficiency for sample preparation. Whether you’re working with metabolomics, enzymatic activity, or DNA extraction, Precellys ensures that every step of your research is streamlined, reliable, and ready for success.   Appetizer:optimize metabolomic studies from […]

The quality and efficiency of RNA and DNA extraction are essential factors in molecular biology research, diagnostics, and clinical applications. Whether in research laboratories, medical testing, or biotechnology facilities, optimizing RNA and DNA extraction protocols ensures reliable, high-quality results. The extraction techniques can vary based on the sample type and complexity, with methods including mechanical […]

In this study, researchers examine the effects of two drugs, everolimus and metformin, on triple-negative breast cancer.  Everolimus blocks a protein called mTOR, while metformin blocks part of the mitochondria, the energy powerhouses of cells. They found that everolimus reduced products of the tricarboxylic acid (TCA) cycle, a key energy-producing process, and inhibited an enzyme called pyruvate […]

Obtaining viable single cells from lung tissue is essential for understanding respiratory function and disease mechanisms. Despite its importance, isolating these cells remains challenging. Bertin Technologies’ Precellys Multi Tissue Dissociation kit, in conjunction with the Precellys Evolution Touch (or Precellys Evolution), offers an effective solution for dissociating lung tissues into single cells. In our recent […]

Bertin Instruments will attend PITTCON Conference & Expo 2017, the world’s leading annual conference and exhibition on laboratory science to showcase its new InCellis Cell Imager and Precellys tissue homogenizers at the McCormick Place (West Hall), booth #938, from 5 to 9 March. About InCellis Cell Imager: Cell biologists need to generate cell images in […]

With more than several thousand publications in under two years, CRISPR-Cas9 revolutionized the science world and more particularly cellular and molecular biology. CRISPR-Cas9 technology allows genetic editing through mutation. For example, this leads to the generation of Knock-In or Knock-Out mice for animal studies [1]. Introducing mutation requires some controls to check the validity and […]